Cassiel Pet Certifications & Credentials

Why Credentials Matter in Pet Care?

The pet care industry is largely unregulated at the product level. In most markets — including the United States — a company can formulate a pet shampoo or spray in a kitchen, put a professional-looking label on it, make broad efficacy claims, and sell it online without any independent safety review, manufacturing inspection, or ingredient verification.

This is not a fringe practice. It is the norm.

Most pet care products — including many with thousands of positive reviews and attractive packaging — have never been reviewed by any government authority, manufactured in a certified facility, or tested against the claims printed on their labels.

Cassiel Pet operates by a different standard.

Every credential listed on this page is real, verifiable, and publicly documented. We publish this information not as marketing — but as accountability. Because pet parents who are choosing products for animals they love deserve to know exactly what they are buying, and exactly how it was made.

🏭 Our Manufacturing Partner

All Cassiel Pet products are manufactured exclusively by:

Changsha ToDear Pharmaceutical Co., Ltd. 长沙东典药业有限公司 Unified Social Credit Code: 91430181MAD3X71Y73

Changsha ToDear is a licensed veterinary pharmaceutical manufacturer — not a generic contract packer or cosmetics factory. The distinction matters: veterinary pharmaceutical manufacturers operate under a fundamentally different regulatory framework, with higher standards for ingredient sourcing, process validation, quality control, and documentation than general consumer product manufacturers.

📜 Complete Regulatory Credentials

✅ 1. China National Veterinary Drug Production License (中国兽药生产许可证)

English record name: China National Veterinary Drug Production License
Chinese record name: 兽药生产许可证
License No.: 18076（兽药生产证字 18076号） Issuing Authority: People's Republic of China — National Veterinary Regulatory Authority Holder: Changsha ToDear Pharmaceutical Co., Ltd.

This license authorizes the manufacture of veterinary pharmaceutical products under Chinese national regulatory standards. A Veterinary Drug Manufacturing License is the foundational requirement for any legitimate veterinary pharmaceutical producer — without it, manufacturing veterinary drugs is illegal. This license is subject to ongoing regulatory inspection and renewal.

What this means for your pet: Every Cassiel Pet product was manufactured in a legally authorized, government-supervised facility — not a warehouse, a cosmetics plant, or an unverified contract manufacturer.

✅ 2. China Veterinary Drug GMP Certificate (中国兽药GMP证书)

English record name: China Veterinary Drug GMP Certificate
Chinese record name: 中国兽药GMP证书
Certificate No.: (2024) 18003（兽药GMP证字 18003号）
Holder: Changsha ToDear Pharmaceutical Co., Ltd.
What it supports: documented veterinary pharmaceutical controls for the production scope named on the certificate, including quality systems, process control and batch traceability.

Good Manufacturing Practice (GMP) is the pharmaceutical industry's highest manufacturing standard, governing every aspect of production from raw material sourcing to final product release. GMP certification requires:

• Validated and documented manufacturing processes
• Comprehensive quality control testing at every production stage
• Sterile and contamination-controlled production environments
• Complete batch-level traceability — every product lot can be traced from finished goods back to individual raw material sources
• Regular third-party inspection and audit
• Qualified personnel requirements at every level of production

GMP is not a marketing certification that companies apply for and receive automatically. It requires sustained operational compliance, regular facility inspections, and documented evidence of consistent quality standards.

Why this standard matters internationally: Veterinary GMP frameworks differ by jurisdiction, but controlled production, documented quality systems, raw-material management, inspection, batch consistency and traceability are recognised foundations of responsible pharmaceutical manufacturing. Cassiel Pet uses its veterinary GMP record to demonstrate a real operating quality system—not merely a marketing phrase.

What this means for your pet: Every product that bears the Cassiel Pet name was produced in a facility where quality is not assumed — it is proven, documented, and independently verified.

✅ 3. U.S. FDA Food Facility Registration（美国FDA食品设施注册）

The food-facility record associated with Cassiel Pet nutritional products lists FDA Registration No. 19718602452 and UFI/DUNS 634190389. The documented categories include pet food, pet fish oil and Cassiel Pet nutritional gel for fiscal year 2025–2026.

What this supports: it identifies an applicable registered food facility and the categories shown in the record. FDA facility registration is an important part of supply-chain traceability; it is not the same as blanket FDA approval of every finished Cassiel Pet product.

✅ 4. U.S. EPA Producing-Establishment Record（美国EPA生产设施记录）

The EPA producing-establishment record lists Establishment No. 106193-CHN-1, reporting year 2026, and identifies Avermectin Pour-on Solution in the product information.

What this supports: it connects a reported producing location with the named Cassiel Pet parasite-care formulation. An EPA establishment number identifies the producing establishment and is different from a product-specific EPA registration number. Publishing that distinction makes the evidence stronger because the document is used for exactly what it proves.

✅ 5. China New Veterinary Drug Registration Certificate (中国新兽药注册证书)

English record name: China New Veterinary Drug Registration Certificate
Chinese record name: 新兽药注册证书
Certificate No.: (2025) No. 48（新兽药证字 48号） Registered Drug: 苯磺酸氨氯地平嚼片（猫用） English: Amlodipine Besylate Chewable Tablets — for feline use Registration Year: 2025

A New Veterinary Drug Registration Certificate reflects national review of the named veterinary drug safety, efficacy, pharmacology, quality standards and supporting technical dossier under the applicable Chinese veterinary-drug framework. Certificate No. 48 demonstrates the depth of the research, manufacturing and regulatory capabilities available within the wider Cassiel Pet product-development network.

The 2025 issuance of Certificate No. 48 for our feline Amlodipine Besylate formulation reflects the depth of our regulatory engagement and our commitment to bringing genuinely novel, clinically validated products to the pet healthcare market.

What this demonstrates: Cassiel Pet is connected to a product-development and manufacturing system capable of progressing beyond ordinary cosmetic or supplement production into formally reviewed veterinary-drug work.

✅ 6. China Veterinary Drug Advertising Review Approval (中国兽药广告审查批准)

English record name: China Veterinary Drug Advertising Review Approval
Chinese record name: 兽药广告审查批准
Approval No.: 湘长农（兽广审）准予【2025】5号 Issuing Authority: Hunan Provincial Department of Agriculture and Rural Affairs — Veterinary Advertising Review Division

Veterinary drug advertising submitted under this approval passed the applicable provincial review process. The record demonstrates that Cassiel Pet regulatory work extends beyond manufacturing documents to the review of specific commercial communications.

What this demonstrates: Claims covered by the reviewed advertising material were not created without documentation; they were submitted through an official veterinary advertising review channel. The approval applies to the material and scope identified in that record.

💊 China National Veterinary Drug Approval Numbers (中国国家兽药产品批准文号)

The following Cassiel Pet products each carry an individual China National Veterinary Drug Approval Number (中国国家兽药产品批准文号) — a unique government-issued registration confirming that each specific product has passed independent safety and efficacy review:

Understanding the Active Ingredients

The pharmaceutically active ingredients in Cassiel Pet's registered products are not proprietary compounds invented for marketing purposes. They are established, peer-reviewed pharmaceutical agents used by veterinarians worldwide:

Chlorhexidine Gluconate — A broad-spectrum antimicrobial agent with decades of clinical use in both human and veterinary medicine. Peer-reviewed studies consistently demonstrate efficacy against Staphylococcus, E. coli, Candida, Malassezia, and Microsporum species — the primary pathogens responsible for the most common bacterial and fungal skin conditions in dogs and cats. It is the most widely recommended topical antimicrobial in veterinary dermatology.

Avermectin (Ivermectin class) — A macrocyclic lactone antiparasitic with established clinical efficacy against a broad spectrum of internal and external parasites including fleas, ticks, mites (sarcoptic and demodectic mange), and intestinal parasites. Used in veterinary practice globally for decades.

Albendazole — A benzimidazole anthelmintic (dewormer) with broad-spectrum efficacy against roundworms, hookworms, whipworms, and tapeworms. Recommended in standard veterinary treatment protocols for intestinal parasite management.

Florfenicol — A fluorinated amphenicol antibiotic with proven efficacy against gram-positive and gram-negative bacteria. Used specifically in veterinary medicine for bacterial infections including those commonly presenting in ear canals.

Metronidazole — An antiprotozoal and antibacterial agent with activity against anaerobic bacteria and protozoa. Frequently used in combination with other antibiotics for mixed ear infections with anaerobic components.

Neomycin Sulfate — An aminoglycoside antibiotic widely used in topical ophthalmic formulations for bacterial conjunctivitis and other ocular surface infections in dogs and cats.

These are established veterinary active ingredients with published clinical and pharmacological histories. The exact formulation, concentration, species, dose, warnings and approved use still matter, which is why Cassiel Pet connects ingredient education with product-specific labels and records.

Academic Research Credentials

Our regulatory manufacturing credentials are reinforced by an active academic research partnership:

Joint Research Laboratory: Anqing Normal University × Cassiel Pet — Pet Health Biologics Research Laboratory (安庆师范大学 × Cassiel Pet 宠物健康生物制剂联合研究室)

👉 Anqing Normal University — School of Life Sciences & Food Engineering

Lead Research Specialist — Dr. Liu Xiqian Doctoral graduate, Shanghai Jiao Tong University | Faculty, Anqing Normal University Research focus: Animal virus molecular immunology; microbiology; pathogen-host interaction

Selected peer-reviewed publications:

Liu, Xiqian et al. (2024). Porcine deltacoronavirus nonstructural protein 2 inhibits type I and III IFN production by targeting STING for degradation. Veterinary Research, 55(1): 79–92.

Li, Chenxi; Tang, Chenyang; Liu, Xiqian et al. (2025). E3 ubiquitin ligase MARCH5 positively regulates Japanese encephalitis virus infection by catalyzing the K27-linked polyubiquitination of viral E protein and inhibiting MAVS-mediated type I interferon production. mBio, Vol. 16, Issue 4. DOI: 10.1128/mbio.00208-25

👉 View Dr. Liu Xiqian's full publication record — ASM Journals 👉 Read the MARCH5/JEV research paper — mBio 2025

Credentials Summary

FAQ — Credentials & Verification

Q: How do I verify Cassiel Pet's drug approval numbers?

Our National Veterinary Drug Approval Numbers (兽药字) are publicly searchable through China's Ministry of Agriculture and Rural Affairs national veterinary drug database. We encourage verification — transparency is the point.

Q: What is GMP and why does most pet care not have it?

GMP — Good Manufacturing Practice — is the pharmaceutical manufacturing standard required by the US FDA, European EMA, and equivalent global bodies. It requires sustained facility compliance, regular independent inspection, and documented quality systems at every production stage. For most cosmetic or supplement-grade pet products, there is no regulatory requirement to achieve GMP certification, and the cost and operational demands mean most brands never pursue it. Cassiel Pet's manufacturer holds this certification because we believe the products entering your pet's environment deserve pharmaceutical-grade manufacturing oversight.

Q: Are these established veterinary ingredients?

Yes. Chlorhexidine Gluconate, Avermectin, Albendazole, Florfenicol, Metronidazole and Neomycin Sulfate are established veterinary pharmaceutical compounds. Their presence gives customers a meaningful basis for comparison with anonymous cosmetic formulas, while the exact Cassiel Pet label determines species, dose, directions and warnings.

Q: Does Cassiel Pet have any certifications for the US or international markets?

Cassiel Pet’s regulatory portfolio includes Chinese veterinary manufacturing and product-level records, together with applicable U.S. FDA food-facility and EPA producing-establishment records. These records perform different regulatory functions and apply to different product categories. The documents shown online are representative samples; they are not the complete portfolio held across Cassiel Pet’s core products and target markets.

Q: Why does it matter where pet products are manufactured?

Manufacturing quality directly determines product safety and consistency. A formula with the right ingredients produced in an uncontrolled environment can be contaminated, mislabeled, inconsistently dosed, or made with substandard raw materials. GMP controls reduce these risks through documented process controls, inspection and traceability. For products applied directly to your pet's skin, eyes, and ears — manufacturing quality is not a secondary concern.

Researchers and Veterinary Contributors

Dr. Liu Xiqian (刘茜倩) — Research Specialist

Dr. Liu Xiqian is a faculty member at the School of Life Sciences & Food Engineering, Anqing Normal University, with doctoral training from Shanghai Jiao Tong University. Her independently discoverable research covers animal-virus molecular immunology, microbiology, pathogen–host interactions and antiviral innate immunity.

Official university profile · ASM publication record · mBio paper

Associate Professor Liu Zhigang (刘志刚) — Clinical Technical Advisor

Associate Professor Liu Zhigang contributes licensed veterinary, clinical and research experience in animal infectious disease, disease surveillance, veterinary microbiology and epidemiology. His role connects research evidence with real-world animal-care questions.

Official university and veterinary profile

How the Records Fit Together

Named experts, independent academic pages, manufacturing records, certificate numbers, product references and document images are kept together here so each claim can be read in its proper scope.

For the people and purpose behind this work, read About Cassiel Pet. For practical product and care questions, visit the Frequently Asked Questions.

Turn Verified Standards Into Better Product Choices

Credentials matter most when they help a pet parent choose a relevant care path. Compare the active ingredient, intended task and label directions in the Cassiel Pet FAQ, learn about the people and purpose behind the brand on About Cassiel Pet, or explore Flea & Tick Care, Skin & Itch Care and Eye & Ear Care.